AI Governance Infrastructure

Every AI
interaction.
On record.

GMP sites are deploying AI. Regulators are arriving to inspect it. We're building the infrastructure that captures every interaction, validates it against your governance policy, and produces the audit trail your quality team needs.

duxbio · audit-stream · live
0
Interactions logged
0
Policy flags raised
0
Reports generated
Compliance status
Designed for GMP / Annex 22
21 CFR Part 11 Audit Trail
Lite · Minimal Deployment
Enterprise · On-Premise
The Inspection Moment
"Show me what the AI did, what data it touched,
and what human oversight occurred_"

Most sites today cannot answer this question.

FDA Inspector · GMP Manufacturing Floor

AI is on the floor.
The paper trail isn't.

Quality teams are caught between two pressures: pressure to adopt AI tools for efficiency, and regulatory pressure to document every decision those tools make. Right now, there is no infrastructure that bridges them.

01 · The deployment reality
AI is already in use

LLMs and AI-assisted platforms are already in use on GMP sites — often without formal IT governance. Quality teams are adopting tools their QMS was not designed to track.

02 · The regulatory shift
Inspectors are catching up

EU GMP Annex 22 — the first AI-specific pharmaceutical regulation — is in consultation now. FDA issued draft guidance in 2025. The window to implement governance proactively, rather than reactively after a finding, is closing.

03 · The gap
Nothing exists to bridge them

QMS vendors validate processes — not AI interactions. Security tools flag data leaks — not GxP taxonomy violations. Consultancies write SOPs — not audit trails. No tool currently produces inspection-ready AI documentation.

18–36

The Window

Months before Annex 22 finalises — and compliance is no longer a choice.

Sites that implement AI governance ahead of the mandate walk into inspections with evidence. Sites that wait respond to findings. The difference is not the technology — it's the timing.

Annex 22 21 CFR Part 11 GCP GVP ICH E6 / E8
Regulatory Timeline · 2025 → 2028+

The mandate is
forming now.

Jan 2025
FDA Draft Guidance

AI in regulatory decision-making. First formal signal from the FDA.

Mid 2025
EU GMP Annex 22

Enters consultation. First AI-specific pharma regulation globally.

2026 · Now
Proactive Window

Quality directors implement ahead of mandate. The window is open.

2027–28
Annex 22 Finalised

Non-compliant sites face inspection findings. The window closes.

2028+
FDA Follow-On

US AI governance mandated. Full global enforcement begins.

How It Works

Capture. Validate. Document.

Three steps, one inspection-ready output. This is the framework we're building — designed to work regardless of which AI tools your site uses, and regardless of how they are accessed.

Step 01 · Capture

Every interaction.

The system is designed to capture every AI interaction at full fidelity — through a controlled interface for low-footprint sites, or a gateway layer for full-stack coverage. The goal: nothing missed, regardless of how AI is being accessed on site.

Full prompt + response log Timestamp + user attribution Tool + model identification
Step 02 · Validate

Against policy.

Each captured interaction will be classified against a GxP life-sciences taxonomy, checked against your site's governance policy, and flagged for data sovereignty issues — before the interaction completes.

Policy exception flagging Data sovereignty enforcement Risk classification
Step 03 · Document

Inspection-ready.

The output is a single inspection report — regardless of which AI tool generated the interaction or how it was accessed. One SOP. One validation document. One training record. Designed to hold up in front of an inspector.

21 CFR Part 11 audit trail Human oversight record Data lineage map
Product Tiers

Start where you are.
Scale as you grow.

Both tiers are designed to produce the same inspection output. Deployment approach scales with your site's IT complexity and existing AI tool footprint.

DuxBio Lite
Lite

A controlled interface for LLM access. Minimal deployment. Built to get sites capturing quickly.

Users access leading LLMs through DuxBio's controlled interface — interactions are routed through our infrastructure and logged automatically
Designed to require minimal IT involvement — the goal is to be operational without a formal procurement or infrastructure project
Audit trail, human oversight prompts, and Annex 22-aligned inspection report generated for every session
Suited to biotech and SME sites beginning their AI governance journey — and designed as a natural on-ramp to Enterprise
Pricing on request
Get in Touch →
Who It's For

Built for the people who walk into the inspection room.

QD Quality Director / VP Quality
You're accountable for everything that happens on your GMP floor — including what the AI did.

We're building the documentation layer your QMS was never designed to provide — so you can present a complete AI activity record to any inspector, for any tool, from a single report.

RA Regulatory Affairs Lead
Annex 22 is in consultation. You need a defensible answer before it finalises.

Implementing governance proactively positions your site ahead of the mandate — not in remediation after a finding. We're designing DuxBio's output to align with Annex 22 requirements as they are currently drafted.

GM GMP Site / Operations Lead
Your teams are using AI tools. You've been asked to govern them. You need a starting point.

DuxBio Lite is designed to get sites capturing quickly — with minimal IT involvement. Your quality team gets the audit trail they need. Your operations team keeps the tools they're already using.

The question inspectors are already asking

"Do you have a documented process for AI use? Can you show me every AI-assisted decision made in the last 12 months, who authorised it, and what data it used?"

About DuxBio

We've sat on both sides of the inspection room.

DuxBio was founded by people who have worked inside pharma GMP environments and understand the regulatory pressures quality teams face — not as consultants observing from the outside, but as practitioners who lived them.

We combine deep GxP domain knowledge with AI and software expertise. We are not a technology company that discovered pharma — we are pharma people who identified the gap no software company had closed, and are building the infrastructure to close it.

Pharma GMP background — hands-on experience inside regulated manufacturing environments, with direct knowledge of inspection readiness and quality system requirements
AI and software expertise — deep technical knowledge of LLM infrastructure, audit systems, and regulated software development
What we believe
AI governance is not an IT project.

Quality directors should own AI governance, not wait for IT to deliver a solution. We're building DuxBio to be adopted by quality teams directly — with as little IT friction as possible.

The audit trail should be automatic.

Compliance shouldn't depend on users remembering to document their AI interactions. We're building DuxBio to capture at the infrastructure level — so the trail is generated, not manually filed.

One inspection report, regardless of the tool.

Sites use multiple AI tools. Inspectors ask one question. DuxBio is designed to produce one answer — a unified interaction record aligned to GxP standards, regardless of vendor.

Early access partners shape what we build.

We're working with a small number of quality teams in 2026 to develop and validate the product. If you're dealing with this problem now, we'd rather have that conversation than send you a brochure.

Early Access · 2026

Get ahead of
the inspector.

We're working with a select group of quality teams ahead of Annex 22 finalisation. No sales process — just a conversation about your site's AI footprint and whether DuxBio is the right fit.

No sales pitch. We'll reply within one business day.

✓   Request received.
We'll be in touch within one business day.